Protein Purification Reagents and Kits
AdipoGen CTRP5 human rec His
Protein. Human CTRP5 aa 16-243 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Lyophilized from a 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. CTRP5 C1qTNF-related protein 5 C1QTNF5 belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase AMPK in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration LORD.
AdipoGen GITRL Soluble hrecHis
Protein. The extracellular domain of human GITRL aa 74-199 is fused at the C-terminus to a His-tag. Source HEK 293 cells. Endotoxin content <0.06EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in PBS. Purity >90% SDS-PAGE. GITRL Glucocorticoid-induced TNF receptor ligand is expressed on dendritic cells DC, monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues e.g. testis. GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
AdipoGen ACBP h rec His
Recombinant protein. Human acyl-CoA-binding protein aa 2-87 is fused at the C-terminus to a His-tag. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. Acyl-coenzyme A CoA-binding protein ACBP is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A CoA-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor DBI that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid GABA type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy energy deficiency in different organisms including mouse and human. ACBP levels correlate with human body mass index BMI.
eMolecules 395101-67-4 | ChemScene | 3-Bromo-1H-indazole-5-carbonitrile | 100mg | 572175836 | CS-0042024 | MFCD09263218 | 222.045 | C8H4BrN3
Ambeed | 5-Chloro-2-hydroxyphenylboronic acid | 1g | 572830818 | A807359 | 89488-25-5 | MFCD06659863 | 172.370 | C6H6BClO3
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Genscript Corporation CD46 His Canine
CD46 was discovered in 1986 during a search for novel C3b-binding proteins CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack
Genscript Corporation CD4/LEU3 Biotin His Avi
CD4 also known as L3T4 T4 and W3/25 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes It is a standard phenotype marker for the identification of T cell populations Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses In T-cells functions primarily as a coreceptor for MHC class II molecule peptide complex
Genscript Corporation DNAM-1/CD226Biotin His Av
DNAX accessory molecule-1 (DNAM-1) also known as CD226 is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily DNAM-1 mediates cellular adhesion to other cells bearing its ligands CD112 and CD155 and cross-linking DNAM-1 with antibodies causes cellular activation Furthermore DNAM-1 can interact with PVR and PVRL2
Cayman Chemical 5-chloro nI 10mg
A derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group; intended for forensic and research applications
![eMolecules 1256584-80-1 | ChemScene | 9-Ethyl-8-iodo-66-dimethyl-11-oxo-611-dihydro-5H-benzo[b]carbazole-3-carbonitrile | 100mg | 572224288 | CS-M1357 | MFCD22124656 | 440.284 | C21H17IN2O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502439166.PNG-250.jpg)
eMolecules 1256584-80-1 | ChemScene | 9-Ethyl-8-iodo-66-dimethyl-11-oxo-611-dihydro-5H-benzo[b]carbazole-3-carbonitrile | 100mg | 572224288 | CS-M1357 | MFCD22124656 | 440.284 | C21H17IN2O
AstaTech | 3-(TERT-BUTOXYCARBONYL)THIAZOLIDINE-2-CARBOXYLIC ACID | 0.25g | 438641065 | O10893 | 95.000 | 141783-63-3 | MFCD01569306 | 233.280 | C9H15NO4S
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Abcam His-Tag Protein Purification Column (Pre-packed, 5 x 1ml) - AminTrap, 5UNIT
His-Tag Protein Purification Column (Pre-packed, 5 x 1ml) - AminTrap (ab270528) is a simple and easy ready to use chromatography medium for purifying His-tagged proteins that have been expressed in series of expression vectors, such as E.coli., yeast, insect cells and mammalian cells.
The product is subject to the following: Abcam Restricted Use Statement
Genscript Corporation EpCAM/TROP1Biotin His Avi
Epithelial Cellular Adhesion Molecule (EpCAM) also known as KS1/4 gp40 GA733-2 17-1A and TROP 1 is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF like repeats a 23 aa transmembrane segment and a 26 aa cytoplasmic domain
eMolecules 2091134-68-6 | Medchem Express | Golidocitinib | 5mg | 448038983 | HY-107361 | 489.584 | C25H31N9O2
Ambeed | 9-Allyl-9H-carbazole | 1g | 491625841 | A154916 | 3998-04-7 | MFCD00093414 | 207.276 | C15H13N
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Genscript Corporation MSLN/Mesothelin296-591 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Genscript Corporation TROP-2/TACSTD2 His Cynomolgu
Trop-2 also known as epithelial glycoprotein-1 antigen (EGP-1) is a protein that in humans is encoded by the TACSTD2 gene Mutations of this gene result in gelatinous drop-like corneal dystrophy an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness
![eMolecules 898746-50-4 | 5-iodo-1H-pyrrolo[2,3-b]pyridine | Pharmablock | MFCD06659679 | 244.035 | C7H5IN2 | 97.000 | Ic1cnc2[nH]ccc2c1 | 25mg | 586137287](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502433372.JPG-250.jpg)
eMolecules 898746-50-4 | 5-iodo-1H-pyrrolo[2,3-b]pyridine | Pharmablock | MFCD06659679 | 244.035 | C7H5IN2 | 97.000 | Ic1cnc2[nH]ccc2c1 | 25mg | 586137287
5-iodo-1H-pyrrolo[2,3-b]pyridine | Pharmablock | 898746-50-4 | MFCD06659679 | 244.035 | C7H5IN2 | 97.000 | Ic1cnc2[nH]ccc2c1 | 25mg | 586137287